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Terrible Two: Eminem Teams Up with Stewie

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In case you couldn’t tell from his bloody, horrific new music video for “3 A.M.,” Eminem apparently has a sense of humor. And he hopes to convey it to America this Sunday when he gets animated and joins The Family Guy‘s conniving baby man Stewie Griffin to host Animation Domination, FOX’s comedy block also featuring episodes of The Simpsons, American Dad!, and King of the Hill.

“I’m a big fan of talking babies and their humor,” Em, a.k.a. Marshall Mathers, explained.

Stewie had this to say about Mr. Mathers: “I was just about to meet him, but after I shook hands with his stylist, his assistant, his lawyer, his bodyguard, his other bodyguard, his photographer, his manager, his hanger-on, his flower girl, his driver, his videographer, his notary, his historian, his her-storian, his texter and his own greased-up deaf guy, I got the swine flu.”

The animated version of Em, with voice over provided by the real hip-hop star, airs May 17 at 8 P.M. Also that night, the duo will take to MySpace Music (which has the same parent co. as FOX) to make a special announcement. Hopefully they’ll debut a video of the duo trading rhymes about one of the many things they have in common, like, say, mommy issues or violent tendencies.

Eminem’s new album, Relapse, drops May 19. He’ll perform on Jimmy Kimmel Live Friday May 15, and the following Tuesday and Friday.